High Fidelity Periodontal Regeneration
The first regenerative construct that recapitulates the neural-first developmental hierarchy
Neural-first regeneration, 4-signal construct, hydrogel technology
$4.2B market opportunity, business model, use of funds
510(k), BLA pathway, clinical milestones
Scaling strategy, vertical integration, domestic sourcing
Gengyve pioneered the fundamental science of neural-first periodontal regeneration. Spring Leaf represents the commercialization platform—translating breakthrough research into clinically-validated, FDA-cleared regenerative constructs.
Neural ingrowth initiates the regenerative cascade
Vascular network follows neural pathways
Functional periodontal ligament with proper fiber orientation